Before DNA is segregated during cell division, chromosomes are held near the center of the cell by the mitotic spindle, which connects to the chromosomes by a structure called kinetochores. Kinetochores can sustain remarkable amounts of tension to stabilize the geometry of the cell division machinery.

I am very happy to have my drawing accompany a press release presenting an exciting Nature Communications paper on tension forces at kinetochores!

Mitotic Spindle
To segregate our DNA during cell division, the mitotic spindle pulls the duplicated chromosomes towards opposite poles of the cell.