Handcuffs for CRISPR – my new drawing for a Molecular Cell paper!
CRISPR Handcuffs: Anti-CRISPR protein AcrIIA6, shown as handcuffs, sequesters and inhibits two Cas9 molecules (red), while a naturally resistant variant (green) is able to cleave its target DNA.

Handcuffs for CRISPR – my new drawing for a Molecular Cell paper!

You may not see it, but an evolutionary battle is being waged all around us between bacteria and the viruses that target them. This drawing depicts an exciting new discovery…

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My Nature Genetics cover illustrating a rearranged genetic landscape!
A Rearranged Genetic Landscape: The pyramids and their altered reflection illustrate how changes to chromatin topology in wild-type and rearranged Drosophila chromosomes have surprisingly little effect on the gene expression landscape. Nature Genetics cover, August 2019

My Nature Genetics cover illustrating a rearranged genetic landscape!

A new paper in Nature Genetics challenges the current model of how the genome’s 3D organisation controls gene expression. Using Drosophila fruit flies that carry rearranged chromosomes, researchers found that…

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An RNA Snapshot of the Past and Present!
An RNA Snapshot of the Past and Present: A new method called 'NASC-seq' can distinguish old and new RNA in a single cell.

An RNA Snapshot of the Past and Present!

When our cells respond to stimuli or differentiate, they change their gene expression dramatically and modify RNA transcription to regulate their genes. One way to monitor gene regulation is to…

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EMBO Reports cover – stabilizing mRNA strands for memory formation!
Stabilizing mRNA Strands for Memory Formation: This drawing illustrates how RNA-binding protein Gadd45α stabilizes long mRNAs for memory formation. EMBO Reports cover, June 2019.

EMBO Reports cover – stabilizing mRNA strands for memory formation!

Presenting my new EMBO Reports cover - stabilizing mRNA strands for memory formation! Learning and forming memories are fundamental processes essential for survival, requiring precise regulation of memory-related genes. This…

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A Pac-Man Toxin in Tuberculosis!
A Pac-Man Toxin in Tuberculosis: A newly discovered toxin triggers cell death by 'eating up' the NAD+ within the bacterium.

A Pac-Man Toxin in Tuberculosis!

Tuberculosis is a serious infectious disease and one of the leading causes of death worldwide. The disease-causing bacteria, called Mycobacterium tuberculosis, are depicted in the drawing in red. To overcome stress…

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